Sex-Linked Inheritance: Male & Female Expressions

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Discussion Overview

The discussion revolves around the inheritance of eye color in a hypothetical organism, specifically examining whether the trait is sex-linked or autosomal. Participants analyze the outcomes of specific crosses between red-eyed and white-eyed individuals, exploring the implications for male and female progeny.

Discussion Character

  • Homework-related
  • Debate/contested
  • Conceptual clarification

Main Points Raised

  • One participant presents a scenario where a white-eyed male is crossed with a red-eyed female, leading to all red-eyed males and white-eyed females, questioning the nature of the trait.
  • Another participant suggests that the trait could be either sex-linked or autosomal, prompting further examination of the evidence.
  • A third participant argues against the trait being sex-linked, citing the results of the reciprocal cross which produced only red-eyed progeny, thus invalidating the first three options presented.
  • This same participant claims that the trait is autosomal and points out a potential mistake in the interpretation of incomplete penetrance in the context of the first cross.
  • Another participant questions the reasoning behind the observed sex differences in progeny when crossing a white-eyed male with a red-eyed female, seeking clarification on the apparent contradiction.

Areas of Agreement / Disagreement

Participants exhibit disagreement regarding whether the trait is sex-linked or autosomal, with multiple competing views presented. The discussion remains unresolved as participants explore different interpretations of the genetic outcomes.

Contextual Notes

There are limitations in the assumptions made about the nature of the trait, particularly regarding the definitions of sex-linked versus autosomal inheritance and the implications of incomplete penetrance. The discussion does not resolve these complexities.

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Homework Statement


In an organism allele for red eye colour is dominant over allele for white colour. A cross is made between a white eyed male and a red eyed female. In the progeny all males are red eyed and females are white eyed. The reciprocal cross leads to all red eyed progeny. Based on the above information choose the correct statement.

1. This is a sex linked trait and the male is homorphic sex
2 This is a sex limited trait and the male is the sex limited trait.
3 This is a sex linked trait and the female is the homorphic sex.
4 This is a case of autosomal inheritance with incomplete inheritance.2. The attempt at a solution
Male:WW x Female:RW --- Red males RW & White females WW

Male:RW/RR x Female:WW ---- RW red progenies, WW progenies are not expressed hence incomplete penetrance.

I don't have the answer. Is it correct?
 
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Well, the first thing to consider is whether you think the trait is sex-linked or autosomal.
 
The trait is not sex linked because in reciprocal cross there are no white male progenies, all are red. So the first 3 options are not valid. The trait is autosomal.*Option four has a mistake: This is a case of autosomal inheritance with incomplete penetrance

In the first cross, red females and white males are also possible, but it doesn't appear in the F2 gen, so we can say there is incomplete penetrance.
 
SanjuktaGhosh said:
The trait is autosomal.
Then why is there a sex difference when breeding a white eyed male and a red eyed female?
 

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