Insulin & Glucagon: Negative Feedback for Blood Sugar

[JimmyRay]

Hi, I want to know how the Insulin/Glucagon hormones act as negative feedback.

Blood sugar goes up, insulin is created, blood sugar goes down, glucagon is created, blood sugar goes up again, and they basically compete with each other to maintain homeostasis, right? But how is this negative feedback.

 

[Dr.Brain]

Insulin hormone is secreted by Pancreas. Insulin mainly encourages the cells to absorb sugars/carbohydrates from the blood. Pancreas secrete Insulin , but when sugar has been absorbed by the cells in apt. amount , and there is just enuff sugar as needed by the body , the overproduction of Insulin gives a negative feedback to previous reactions , due to which pancreas are no mor stimulated by the brain to produce insulin. But when sugar/CarboH levels are again on the increase , Pancreas are again stimulated to produce Insulin which helps cells absorb the sugar/CarboH . In diabetic patients , it maybe the case ,that cells are not being stimulated properly , or there is no coordination between insulin production and pancrea-stimulation.