##\int x^3 \sqrt{4x^2 - x^4}dx = \int x^4 \sqrt{4-x^2}dx \hspace{100px} ##(1)
Let x = 2sinu and dx = cosu du so (1) becomes
##\int (2sinu)^4 \sqrt{4 - 4sin^2u}(2cosu) du \hspace {100px}##. (2)
Gathering up factors of 2 (and please fix if I get it wrong) (2) becomes
## 2^6\int (sin^4u)(cos^2u)du = 2^6\int (sin^4u)(1 - sin^2u)du = 2^6\int (sin^4u - sin^6u)du## (or you can do it in cosines if you prefer).
There are a number of ways to integrate this, but one approach is to deflate the powers of sin by using the half angle formulas:
##sin^2u = \frac{1-cos(2u)}{2}\text { and } cos^2u = \frac{1+cos(2u)}{2}. ## You will have to use this several times but eventually you will get down to something you can integrate. Along the way, you will shed the various powers of 2 that accumulated.
When you finally get down to the definite integral, if you are not getting the right answer, let me know. We'll go over it very carefully.
If this problem was given to you in a first year calc course, it does seem a bit much. I have played around with it to see if I could find an easy solution, but so far I haven't. If your ##x^3## were ##x^{3/2}## it would be much easier; maybe you should double check, just in case that was it.