Dismiss Notice
Join Physics Forums Today!
The friendliest, high quality science and math community on the planet! Everyone who loves science is here!

Intramolecular cyclization of triflate/aniline

  1. Dec 4, 2007 #1
    I was wondering if anyone knew of any good catalysts to use for the intramolecular cyclization of a molecule containing -oTf and -NH2 (aniline) moieties. The only references I can find for such reactions between a triflate and an aniline -NH2 only involve 2 separate molecules. Would the same conditions work for an intramolecular rxn?
  2. jcsd
  3. Dec 5, 2007 #2


    User Avatar
    Science Advisor
    Homework Helper
    Gold Member

    What product are you after? An amide? A secondary amine?
  4. Dec 5, 2007 #3
    Secondary amine.

    I was going to try something like Pd dba and DPPF.
Know someone interested in this topic? Share this thread via Reddit, Google+, Twitter, or Facebook

Have something to add?

Similar Discussions: Intramolecular cyclization of triflate/aniline