Is haemosiderin always haemoglobin derived?

[sameeralord]

Hello everyone,

Haemosiderin definition says that it is a pigment that occurs when there is a local or systemic excess of iron. Does that mean excess iron deposition can cause haemosiderin pigment, I mean you don't alway need macrophages to eat Hb and make it, just iron is enough. Thanks

 

[Ryan_m_b]

Just to clarify are you asking if excess iron is the cause of haemosiderin synthesis? I don't find your post clear to understand.