Is the Thymus Still Relevant in Adulthood and Laboratory Safety?

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Discussion Overview

The discussion centers on the relevance of the thymus gland in adulthood, particularly in relation to its function and presence in the body as one ages. It also touches on laboratory safety concerning the chemical acetylacetone and its potential health hazards.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested

Main Points Raised

  • One participant notes that the MSDS for acetylacetone lists the thymus as a target organ, which they find unusual compared to more commonly listed organs like the liver or central nervous system.
  • Another participant suggests that the thymus does not completely disappear with age but rather atrophies, becoming smaller over time while still retaining some importance in immune function.
  • A third participant agrees that the thymus atrophies and primarily aids in immune function during infancy and childhood, stating that while little remains in adulthood, it is still present in some form.
  • A fourth participant humorously comments on the culinary aspect of the thymus, referring to it as "sweetbreads."

Areas of Agreement / Disagreement

Participants generally agree that the thymus atrophies with age and retains some presence in adulthood, but there is no consensus on its current relevance or importance in adult health.

Contextual Notes

Some statements rely on varying interpretations of the thymus's role and significance, and there are uncertainties regarding the extent of its atrophy and function in adults.

Who May Find This Useful

This discussion may be of interest to those studying immunology, laboratory safety, or the physiological changes that occur with aging.

lisab
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I work with acetylacetone in my lab. The MSDS, in the Health Hazard section, lists the target organ as the thymus.

I don't think I've ever seen the thymus listed in any MSDS as a target organ. Usually, it's the liver, or the central nervous system.

I looked into what the thymus does, and some sources stated that it basically disappears after adolescence. Is this true? I'm 44; do I have any thymus left?

I still wear all the PPE I need to, by the way.
 
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From what I've read some months ago, it doesn't disappear with age, but get atrophied. In other word, it's getting smaller and smaller till reach an almost stable length. I think the Thymus is important in new born (it creates lymphocytes), but loses importance as other glandes produce lymphocytes. It has a similar role to the tonsils. Therefore I think you can live without a Thymus, but it's better not to. (Since we might not know everything about it).
 
Yes, as fluidistic mentioned, the thymus atrophies with age. It's believed to primarily assist with immune function in infancy/childhood, and particularly with development of the immune system. In adulthood, there is very little of it left, but you do have one (in most of the aged cadavers we study in the anatomy lab, it's barely recognizable as it looks a lot like a few lymph nodes in fascia, but it's still there).
 
It's also very tasty (sweetbreads).
 

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