The time-energy uncertainty relation gives a minimum value for the product of two numbers:
1) the uncertainty in the energy of a system
2) the typical time interval over which the state of the system changes appreciably
So systems with sharply defined energy change only slowly. Conversely fast-changing systems have poorly defined energies. Perhaps the best example is atomic energy levels. Electrons in excited states will decay back to the ground state by emitting a photon after some typical lifetime. As a result the excited energy levels of an atom have slightly uncertain energies, with uncertainty inversely proportional to the lifetime. This is observed as a slight broadening of spectral lines, because photons from this transition can actually be emitted with a range of energies instead of one sharply defined energy (note that there are also other effects that broaden spectral lines).
How do we define "the typical time interval over which the state of the system changes appreciably?" It's something like this. Pick any observable X. X has some expectation value and some uncertainty. The time interval of interest is the time it takes for X's expectation value to change by more than its uncertainty.
I think that Griffiths, for one, has a somewhat careful discussion of the time-energy uncertainty relation.