Metabolism of HFCS & Margarine: Health Impacts

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    Food Metabolism
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SUMMARY

The discussion focuses on the metabolism of high fructose corn syrup (HFCS) and margarine, emphasizing their contributions to inflammation and obesity. Participants highlight that HFCS is metabolized exclusively by the liver, leading to fat accumulation and potential metabolic syndrome. The conversation references peer-reviewed articles, particularly from the American Journal of Clinical Nutrition, to support claims about the health impacts of these ingredients. The need for a clear understanding of metabolism, including the chemical reactions and pathways involved in the digestion and absorption of these substances, is underscored.

PREREQUISITES
  • Understanding of metabolic pathways and processes
  • Knowledge of the composition and chemical reactions of HFCS and margarine
  • Familiarity with peer-reviewed scientific literature
  • Basic concepts of obesity and metabolic syndrome
NEXT STEPS
  • Research the metabolic pathways of fructose and its impact on liver function
  • Study the role of margarine in inflammation and its metabolic effects
  • Examine peer-reviewed articles on the health impacts of HFCS
  • Learn about the enzymes involved in the digestion of sugars and fats
USEFUL FOR

Nutritionists, health researchers, dietitians, and anyone interested in the metabolic effects of food ingredients like HFCS and margarine on health.

UnD3R0aTh
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Hello,

I'm asked to write about the following: "High fructose corn syrup and margarine are two commonly used food ingredients that contribute to both inflammation and obesity."

Write one page each on the metabolism of each of these foods in your body, and cite at least one recent paper (peer reviewed) on their impact on your health.

Can you please help me understand what is needed? What is meant by metabolism? Where can I find peer reviewed articles? Thanks.
 
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What have you found on your own? Surely you have researched this since you are supposed to write about it.
 
I found the articles, but I don't get metabolism, am I supposed to write on how sugars and fats digested, absorbed and and used in the body?
 
it's not that i don't get metabolism, it's a broad term, i don't know what's needed
 
UnD3R0aTh said:
Hello,

I'm asked to write about the following: "High fructose corn syrup and margarine are two commonly used food ingredients that contribute to both inflammation and obesity."

Write one page each on the metabolism of each of these foods in your body, and cite at least one recent paper (peer reviewed) on their impact on your health.

Can you please help me understand what is needed? What is meant by metabolism? Where can I find peer reviewed articles? Thanks.

This whole research paper prompt seems loaded, HFCS doesn't contribute to obesity, more calories in than out does.

http://ajcn.nutrition.org/content/88/6/1716S.full He consults for the food and beverage industry, good read though. And check out some of the references.

I'm also pretty sure fructose, glucose, sucrose all cause inflammation, it's not limited to one type of sweetener.

UnD3R0aTh said:
it's not that i don't get metabolism, it's a broad term, i don't know what's needed

It's wondering how HFCS is absorbed in the body, what happens...ect.
 
Student100 said:
This whole research paper prompt seems loaded, HFCS doesn't contribute to obesity, more calories in than out does.

http://ajcn.nutrition.org/content/88/6/1716S.full He consults for the food and beverage industry, good read though. And check out some of the references.

This issue is currently under some debate in the scientific community. Although obesity is clearly caused by eating more calories than our body uses, obesity is not a health problem in itself; rather, obesity is a risk factor for various other health problems such as type II diabetes and cancer. Collectively, the negative health effects associated with obesity are sometimes referred to as metabolic syndrome.

Research over the past decade or so has suggested consumption of fructose is a major contributor to metabolic syndrome, so calories from foods containing fructose such as sugar or HFCS, are worse that calories from other sources. This is because fructose is metabolized exclusively by the liver, leads to build up of fat in the liver, which is though to contribute to metabolic syndrome. See, for example, my post in a previous thread on the topic for some links to papers studying this issue (the thread may be relevant to the OP as well).
UnD3R0aTh said:
it's not that i don't get metabolism, it's a broad term, i don't know what's needed
A good starting point would be to say, what types of molecules compose each of the two substances, and what chemical reactions are involved in breaking these substances down in order to produce energy and/ store them in the body. Good questions to consider might be where in the body are each of these chemical reactions occurring, what enzymes are involved in the reactions, and what metabolic pathways the products of the reactions feed into.
 

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