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Mitochondrial uncoupling and cancer?

  1. Jul 11, 2017 #1
    I've been pondering over whether it is possible to cause cancerous cells to self-destruct by increasing the metabolic rate of an organism via mitochondrial uncoupling of various agents, such as DNP (Dinitrophenolate).

    The rationale is that cancerous cells require much more energy than other surrounding cells and by increasing the metabolic rate of said tumorous cells one can induce accelerated senescence of tumor and cancerous cells. I can't seem to find any studies for the dangerous weight loss agent (DNP); but, it seems that by increasing mitochondrial respiration and energetics via the production of heat would hypothetically cause apoptosis of said cells.

    Thoughts?
     
  2. jcsd
  3. Jul 11, 2017 #2

    jim mcnamara

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    Staff: Mentor

    PF does not support personal theories. Thread locked pending moderation.
     
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