Model for spread of contagious disease.

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    Disease Model
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Discussion Overview

The discussion revolves around modeling the spread of contagious diseases, focusing on mathematical representations and dynamics of infection rates. Participants explore various approaches, including the use of logistic equations and transformations of infection proportions.

Discussion Character

  • Exploratory
  • Mathematical reasoning
  • Technical explanation

Main Points Raised

  • One participant suggests defining y as the number of infected persons and y' as the rate of spread, questioning the relationship between infected and non-infected contacts.
  • Another participant proposes modeling the infected proportion p using the transformation x = log(p/(1-p)), suggesting that the rate of change of p is proportional to e^x.
  • A later reply simplifies the model, proposing that the number of contacts between infected and uninfected individuals should be proportional to p(1-p).
  • A reference to a paper discusses mathematical models of epidemic dynamics, specifically the SIR model, and its application to both fictional scenarios and real-world data on influenza.
  • One participant expresses uncertainty about the more complex mathematical explanations provided, indicating a preference for simpler models like the logistic equation.

Areas of Agreement / Disagreement

Participants do not reach a consensus on the best modeling approach, with multiple competing views and varying levels of mathematical complexity presented throughout the discussion.

Contextual Notes

Some participants express uncertainty regarding the mathematical details and their applicability, indicating a range of familiarity with the concepts discussed.

elitewarr
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Hello guys, I am quite unsure in how to start the modeling for population. If I define y as the number of infected persons and y' as the rate of spread is it correct? I see the number of contacts between infected and non infected persons to be equal to the number of infected persons. Otherwise I have no idea how to form the variables.

Thank you.
 
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If p\in(0,1) is the infected proportion, it may be convenient to model things in terms of x=\log\dfrac{p}{1-p}, as the latter (which is in one-to-one correspondence with the former) can take any real value.

It sounds like what is being described is that \dot p is proportional to e^x, so say \dot p = \alpha e^x for some \alpha>0.

Then we can compute \dot x e^x = \dfrac{d}{dt} e^x = \dfrac{(1-p)\dot p - p(-\dot p)}{p^2} = \dfrac{\dot p}{p^2}= \dfrac{\alpha e^x}{p^2}, and so \dot x = \dfrac{\alpha}{p^2}. One can further verify that p = \dfrac{1}{1+e^{-x}}, and so \dot x = \alpha(1+e^{-x})^2.

From the above equation, it's easy to see that:
- x is strictly increasing over time if -\infty<x<\infty, and therefore p is strictly increasing if 0<p<1.
- Therefore, x must converge to something finite or infinite. It's easy to see that it can't converge to anything finite over time. Therefore x\to\infty. Thus p\to 1 as long as 0<p\leq 1.

The only remaining case of p starting at 0 is easy to consider on its own.
 
Oh whoops, it's simpler than that. Disregard.

Number of contacts between infected and uninfected should be proportional to p(1-p) maybe?
 
http://arxiv.org/abs/1311.6376

Mathematical models of epidemic dynamics offer significant insight into predicting and controlling infectious diseases. The dynamics of a disease model generally follow a susceptible, infected, and recovered (SIR) model, with some standard modifications. In this paper, we extend the work of Munz et.al (2009) on the application of disease dynamics to the so-called "zombie apocalypse", and then apply the identical methods to influenza dynamics. Unlike Munz et.al (2009), we include data taken from specific depictions of zombies in popular culture films and apply Markov Chain Monte Carlo (MCMC) methods on improved dynamical representations of the system. To demonstrate the usefulness of this approach, beyond the entertaining example, we apply the identical methodology to Google Trend data on influenza to establish infection and recovery rates. Finally, we discuss the use of the methods to explore hypothetical intervention policies regarding disease outbreaks.
 
Sorry for the late reply. Thank you guys. But I think the simpler version should suffice according to the logistic equation.

And.. I don't rawly understand what you wrote economicsnerd haha.. My knowledge isn't that advanced yet..
 

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