Hello! I'm guessing nanotechnology poses many difficulties, especially when using synthetic materials to manufacture complicated machines on such a small scale. I was thinking, therefore, that, if the mechanisms of protein folding are figured out, then mRNA sequences can be designed to produce 'designed' proteins. The manufacture of these tiny machines can be undertaken by ribosomes. Although I guess that is only part of the problem. Designing the protein is the other difficulty. Nonetheless, is there a role for usurping biological methods for making such small scale 'machines', as proteins often are, in the field of nanotechnology? Designing RNA sequences and using either natural or synthetic ribosomes to construct the desired machine? Hmmmmm. Interesting? Nobahar.