Needing to calculate kDa for Hyaluronic acid

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The discussion centers on calculating the kilodalton (kDa) value for Hyaluronic acid based on provided molecular weight and other parameters. The molecular weight is given as 1.14M, which is interpreted as 1.14 million. To convert this to kDa, the value is divided by 1000, resulting in approximately 1140 kDa. However, further clarification reveals that if the molecular weight is interpreted as 1.14 kg/mol, the correct kDa would be 114, indicating a low molecular weight suitable for specific applications.

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Tarn
Please post this type of questions in HW section using the template and showing your work.
I know very little about chemistry so not sure if this is possible. I am wanting to find out the kDa from the values given in the fact sheet ( I'm not sure exactly what it can be calculated from but these are the values from the fact sheet )
molecular weight 1.14M
bulk density .34g/cm3
limiting viscosity 18.8 dl/g
Just wondering if anyone can calculate the kDa for me as I've spent the last 2 hours trying to work out how to do it but I'm lost!
Thanks :smile:
 
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kDa stands for kilodalton. It's a unit of molecular weight. More precisely, 1 dalton = 1g/mol, and 1 kDa = 1000 Da.
 
kDa is measure of molecular weight. One hydrogen atom mass == 1 Da. Proteins and other macromolecule molecular weights are usually measured in 1000 Da or kDa.

Hyaluronic acid is a polymer: (C14H21NO11)n where n can be a large number. So you have 1.14M, I'm taking that to mean 1.14 million. So divide 1.14 million by 1000 to get kDa. Answer is ~= 1140 kDa.

Edit -- TeethWhitener beat me to it.
 
Thanks for your help. I'm still a bit lost as I have low molecular weight Hyaluronic so it shouldn't be over 1000. But I'm leaning towards M meaning Molar mass which is what it seems to represent which is often measured in g/mol but standard measurement is kg/mol. So if it is 1.14 kg/mol and 1 kDa is equal to 1g/mol then I'm thinking it's 114 kDa which is considered to be in the low range so perfect. If the 1.14 is measured in g/mol then it would be 1.14 kDa which is too low. I've read so much I've gone cross eyed ( the reason I want to know is because kDa under 50 can increase inflammation rather than help it )...I'm hoping I'm on the right track!
 
Where are you getting these numbers from? Is it possible to link to the document or upload a picture?
 

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