Nucleoli and Nucleus: The Relationship and Role in the Nuclear Matrix

[Docscientist]

If nucleoli does not have a clear membrane,wouldn't it get mixed up with substances in the nuclear matrix present in the nucleus ?

 

[Ygggdrasil]

The nucleolus is though to separate itself from the rest of the nucleoplasm via physical mechanisms resembling phase separation (like how oil droplets can separate from water). This is a very active area of research with many new results in the past couple of years. Here's a recent review on the topic: http://www.sciencedirect.com/science/article/pii/S0955067415000435

 

[Docscientist]

phase separation (like how oil droplets can separate from water).

That's the perfect answer.Thank you