# PartB Distribution of coefficent in immiscible solvents

• Fairway
In summary, the conversation discusses lab results for the distribution of coefficients for different substances between water and methylene chloride. The values of K are small compared to caffeine's K of 4.6, and it is questioned whether methylene chloride is polar enough to dissolve ionic substances. It is noted that sodium benzoate does not dissolve in methylene chloride due to its non-polar nature, while other acids such as benzoic acid and succinic acid dissolve in small amounts. The conversation also touches on the concepts of weak and strong acids and the solubility of charged and uncharged forms in both solvents. The question of caffeine's distribution of coefficient is also raised.
Fairway

## Homework Statement

Hey guys, I have lab result here for Distribution of coefficient for the solid between water and metylene chloride

Benzoic Acid: 5mg (Weight of solute in methylene chloride)
45mg (Weight of the solute in water )

Succinic Acid: 1mg (Weight of solute in methylene chloride)
49mg (Weight of the solute in water)

Sodium Benzoate: none ( Weight of solute in methylene )
50mg (Weight of the solute in water)

## Homework Equations

Becaue the volume of methylene chloride and water (2mL each) are the same in my lab,
K (distribution of coefficient)
= (the weight of the solute in methylene chloride)/ (the weight of solute in water)

## The Attempt at a Solution

Benzoic Acid: K=5/45=0.11
Succinic Acid: K=1/49=0.02
Sodium Benzoate: K=0/50=0

Well, I just did what the equation say that but I'm not so sure why the values of K are so small number campare to caffeine K is 4.6 between methylene chloride and water. Thank you so much in advance.

Is methylene chloride polar enough to dissolve ionic substance?

if you are referring to sodium benzoate, it dissoloves in water completely becaue of the inonic bond, I think.

Will it dissolve in methylene chloride?

I don't think sodium benzoate dissolves in methylene chloride becaue methylene chloride is organic compound and non polar. Other acids such as benzoic acid and succinic acid dissolves mostly in Water because they are di-polar but still dissolves tiny amount in methyle chloride.

Not bad. Perhaps you don't have a full picture yet, but you are definitely on the right track.

Benzoic acid is weak, or strong? What happens when it dissociates? What about solubility of charged and uncharged forms in both solvents?

## 1. What is PartB Distribution of coefficient in immiscible solvents?

PartB Distribution of coefficient in immiscible solvents is a method used in scientific research to determine the distribution of a substance between two immiscible solvents. This technique is often used in analytical chemistry and biochemistry to separate and purify substances.

## 2. How does PartB Distribution of coefficient in immiscible solvents work?

In PartB Distribution of coefficient in immiscible solvents, a known amount of the substance is added to a mixture of two immiscible solvents. The substance will then distribute itself between the two solvents based on its solubility and other chemical properties. By measuring the concentration of the substance in each solvent, the distribution coefficient can be calculated.

## 3. What is the significance of PartB Distribution of coefficient in immiscible solvents?

PartB Distribution of coefficient in immiscible solvents is a useful technique in research as it allows for the separation and purification of substances. It can also provide valuable information about the solubility and chemical properties of a substance, which can aid in understanding its behavior in different environments.

## 4. What are some common applications of PartB Distribution of coefficient in immiscible solvents?

This technique is commonly used in pharmaceutical research to determine the distribution of drugs in different body tissues, as well as in environmental studies to understand the distribution and fate of pollutants. It is also used in the production of cosmetics, fragrances, and other consumer products.

## 5. Are there any limitations or drawbacks to using PartB Distribution of coefficient in immiscible solvents?

While PartB Distribution of coefficient in immiscible solvents is a valuable technique, it does have some limitations. It assumes that the substance being studied is fully dissolved in both solvents and does not take into account any chemical reactions that may occur. Additionally, this method may not be suitable for substances with very low solubility or those that are highly volatile.

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