Radiation exposure on person effects on it's reproduction

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SUMMARY

The discussion focuses on the effects of radiation exposure on male reproductive health and the potential risks to offspring. Specifically, individuals exposed to medium to high levels of radiation, such as liquidators from the Chernobyl disaster, may face increased risks of genetic defects in their children. Studies indicate that both male and female reproductive cells can suffer DNA damage from radiation, leading to potential birth defects like trisomy 21. Overall, any individual with a history of significant radiation exposure has a higher likelihood of having children with genetic issues compared to unexposed individuals.

PREREQUISITES
  • Understanding of radiation exposure and its biological effects
  • Knowledge of human reproductive biology, specifically spermatogenesis and oogenesis
  • Familiarity with genetic disorders, particularly those related to environmental factors
  • Awareness of historical nuclear incidents, such as the Chernobyl disaster
NEXT STEPS
  • Research the long-term genetic effects of radiation exposure on human health
  • Explore studies on second-generation effects of Chernobyl victims
  • Investigate the mechanisms of DNA damage during spermatogenesis and oogenesis
  • Review literature on environmental factors contributing to genetic disorders
USEFUL FOR

This discussion is beneficial for medical researchers, geneticists, public health officials, and individuals interested in the implications of radiation exposure on reproductive health and genetic integrity.

Salvador
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Hi, recently this conversation came up with me and one of my friends talking about the nuclear tourists of these days which is becoming more and more part of urban exploration.
Now I tried google but I mainly got results talking about the risk and effects of radiation exposure during birth and while pregnant but I want to know a bit different scenario ,
say for example a person being a male otherwise healthy and capable of reproduction has received some medium maybe even high rates of radiation at some point in his life , like some of the liquidators in the Chernobyl and other nuclear accidents , now after some years or more he and a woman want a child , how high is the risk and if there is any at all that te child will have birth defects and genetic shortcomings due to the males exposure to radiation at some point in his life.

Now for you to better understand my question , I'm talking here about rather high levels of exposure that a person has got sometime in his life and I wonder how does such exposure and cell damage in the body affect the genes given off to a newborn.Thanks.
 
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This is what you are talking about:
https://en.wikipedia.org/wiki/Effects_of_the_Chernobyl_disaster
The article has some issues but is meant for non-scientists.

Here is another:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1173429/

There are studies of second generation Chernobyl victims. You will note that studies done on endemic Russian populations are hard to find in the literature.

In general, females are likely to incur more damage to reproductive DNA. In the ovary at approximately 4 months in utero meiosis in the cells that will become oocytes (eggs) starts and then is put on hold. So from the time a female is inside Mom until she conceives, that DNA material is simply "sitting there" for 20 years or more, exposed to environmental abuse. This is oversimplified but you get the idea. Environmental damage to DNA causes birth defects example: trisomy 21 - a kind of Down's Syndrome. Radiation damage does the same. It causes problems.

Male spermatogenesis takes about 45 days. But in either sex residual DNA damage can be a problem.
https://en.wikipedia.org/wiki/Spermatogenesis

Everyone exposed to high levels of radiation, male or female, is at a greater risk of having children with birth defects and genetic disease than those persons not exposed.
 
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