SARS-CoV-2 Exposure without Infection

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In summary, the conversation discusses a study that found that close contacts who were exposed to Sars-Cov-2 showed no signs of infection but developed memory T cells. The group then questions the extent to which this phenomenon occurs in the population and highlights the need for a more comprehensive understanding of the immune response to the virus. They also express confusion as to why there has not been more research in this area, given the potential longevity of T and B cell immunity compared to vaccine or antibody protection.
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morrobay
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TL;DR Summary
Close contact exposure to Sars-Cov-2 without infection.
From page 6: 'Close contacts who are Sars-Cov-2 exposed are often both NAT negative and antibody negative indicating that Sars-Cov-2 failed to establish a successful infection'. So the exposure generated memory T cells in absence of an infection. I wonder how quantitatively widespread in a population this would be ?https://www.researchgate.net/publication/350192067_Exposure_to_SARS-CoV-2_generates_T-cell_memory_in_the_absence_of_a_detectable_viral_infection
 
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FAQ: SARS-CoV-2 Exposure without Infection

1. What is SARS-CoV-2 exposure without infection?

SARS-CoV-2 exposure without infection refers to being in close contact with the virus that causes COVID-19, but not developing the illness. This can happen when a person is exposed to the virus but their immune system is able to fight it off before it can cause an infection.

2. How does SARS-CoV-2 exposure without infection occur?

SARS-CoV-2 exposure without infection can occur through close contact with an infected person, such as being in the same room or having direct contact with respiratory droplets from coughing or sneezing. It can also occur through touching surfaces contaminated with the virus and then touching your face.

3. What are the symptoms of SARS-CoV-2 exposure without infection?

There are typically no symptoms of SARS-CoV-2 exposure without infection. However, some people may experience mild symptoms such as a sore throat, headache, or fatigue. These symptoms are usually short-lived and do not progress to a full-blown infection.

4. Can a person with SARS-CoV-2 exposure without infection still spread the virus?

It is possible for a person with SARS-CoV-2 exposure without infection to spread the virus to others, although it is less likely than if they were infected. This is because the virus may still be present in their respiratory secretions, even if they do not develop symptoms.

5. How can SARS-CoV-2 exposure without infection be prevented?

The best way to prevent SARS-CoV-2 exposure without infection is to follow recommended guidelines for preventing the spread of COVID-19. This includes wearing a mask, practicing social distancing, washing your hands frequently, and avoiding close contact with people who are sick. Vaccination can also greatly reduce the risk of exposure and infection.

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