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justwild
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In semi-conservative DNA replication why does it happen that one of the new strands formed is discontinuous while other is continuous?
Semi-conservative DNA replication
- Context: Medical
- Thread starter justwild
- Start date
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- Tags
- Dna Replication
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SUMMARY
Semi-conservative DNA replication results in one continuous strand and one discontinuous strand due to the directionality of DNA polymerase. DNA polymerase synthesizes new DNA in the 5' to 3' direction, leading to the formation of Okazaki fragments on the lagging strand. This process occurs at the replication fork, where the double helix unwinds. Understanding these mechanisms is crucial for comprehending genetic replication and stability.
PREREQUISITES- Basic understanding of DNA structure and function
- Knowledge of DNA polymerase and its role in replication
- Familiarity with the concept of replication forks
- Understanding of Okazaki fragments and their significance
- Research the mechanism of DNA polymerase action in detail
- Study the role of Okazaki fragments in lagging strand synthesis
- Explore the implications of replication fork dynamics on genetic stability
- Investigate the differences between leading and lagging strand synthesis
Students and professionals in molecular biology, genetic researchers, and educators seeking to deepen their understanding of DNA replication mechanisms.
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