Local parameters, rest mass, half-life, etc. are the same. No matter how curved your spacetime is, there's a locally inertial frame of reference that looks like flat spacetime.
Anything that involves propagation, results in seriously screwy and complicated dynamics. You get pair production, red shift / blue shift, etc. There's even a basic theorem demonstrating that vacuum in one reference frame is no longer the vacuum in a different reference frame that's accelerated with respect to the first one (Unruh effect). Meaning that, if you have two observers passing through the same area of curved spacetime on different trajectories (e.g. one suspended above a gravitating object by constantly firing engines, and the other in free fall towards the object), one of them might see vacuum and the other might see a soup of particles.