Understanding Bombay Blood Group and its Compatibility for Blood Donation

  • Thread starter Thread starter Suraj M
  • Start date Start date
  • Tags Tags
    Blood Group
Click For Summary

Discussion Overview

The discussion centers around the Bombay blood group, its genetic basis, and compatibility for blood donation. Participants explore the implications of specific genotypes, the presence of H antigens and antibodies, and the ability of individuals with Bombay blood group to receive blood from other types.

Discussion Character

  • Debate/contested
  • Technical explanation
  • Conceptual clarification

Main Points Raised

  • Some participants assert that an individual with genotype IoIo and hh is classified as having the Bombay blood group, not O.
  • There is uncertainty regarding whether individuals with Bombay blood group can accept blood from O-type individuals, with some suggesting that the presence of H antibodies may prevent this.
  • One participant references a source claiming that individuals with Bombay blood group do not express the H antigen, which may lead to complications in blood transfusions.
  • Another participant expresses skepticism about the existence of anti-H antibodies, suggesting that reactions may occur when mixing blood types, but the specifics remain unclear.
  • Conflicting information is noted regarding the presence of H antibodies, with some participants citing their teachers and others referencing Wikipedia and scientific articles.

Areas of Agreement / Disagreement

Participants do not reach a consensus on the compatibility of Bombay blood group with O-type blood or the existence of H antibodies. Multiple competing views and uncertainties remain throughout the discussion.

Contextual Notes

Limitations include varying interpretations of genetic expressions, the presence of H antigens and antibodies, and the reliability of different sources referenced by participants.

Who May Find This Useful

This discussion may be of interest to individuals studying genetics, blood group compatibility, or those involved in transfusion medicine.

Suraj M
Gold Member
Messages
596
Reaction score
39
If an individual has a genotype##I^oI^o## and ##hh## is he considered to be O or bombay blood group?
Also i read that a person with bombay blood group can donate blood to anyone but can accept only from a person of his blood group, why can't he/she accept blood from O-ve?( is there a H antibody?)
 
Last edited:
Biology news on Phys.org
that answers my second question, but contradicts my teachers statement. :(
Thank you anyway,
Anyone for my first question?
 
Suraj M said:
If an individual has a genotype##I^oI^o## and ##hh## is he considered to be O or bombay blood group?

Would that individual be able to accept blood donations from an O-type individual or only from h/h-type individuals?
 
he can take from O, probably, but if there are H antibodies then , no!
My teacher said that There is no H antibody , but wikipedia says that there are..
 
Here's a more definitive reference which says there is an H antigen:

http://www.ncbi.nlm.nih.gov/books/NBK2268/

As I read the article more, it says people may have a deficit of the H so I'm looking for a better article to explain it.

I think your teacher meant to say that people with this blood type don't express the H antigen.
 
Last edited:
I don't feel like trusting that article they say that parabombay blood group have a genotype HH, andthat they have anti-H, which i don't think exists naturally.
I asked another teacher, he said that though there might not be secifically H antibodies, but there will be some reaction, when blood(Hh/HH) is mixed with bombay blood group blood.
 
For your first question, yes, it is Bombay blood group since O has H not h.
There are anti-H antibodies according to my teacher who swears by Wikipedia :P
 
you have some interesting Bio questions :)
 
  • Like
Likes   Reactions: Suraj M

Similar threads

  • · Replies 3 ·
Replies
3
Views
4K
Replies
7
Views
4K
  • · Replies 2 ·
Replies
2
Views
1K
  • · Replies 4 ·
Replies
4
Views
5K
  • · Replies 2 ·
Replies
2
Views
3K
  • · Replies 21 ·
Replies
21
Views
4K
  • · Replies 2 ·
Replies
2
Views
16K
Replies
12
Views
4K
  • · Replies 6 ·
Replies
6
Views
3K
  • · Replies 26 ·
Replies
26
Views
1K