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Understanding Sodium Chloride Co Transporters

  1. Apr 19, 2010 #1
    Hey All,

    In my cellular & tissue biology class our lecturer was talking about neurons. Basically he was explaining that the concentrations are as follows:
    Pottasium: higher inside the cell then outside.
    Sodium: higher outside the cell then inside.
    Chloride: higher outside the cell then inside.

    Naturally there is a drive for potassium to be pumped out and for sodium & chloride to be pumped in.

    He was then explaining that there are ion pumps which move against the concentration gradient. the first is Na-K ATPase - which I have a reasonable understanding of: it requires a free phosphate ion from ATP, and pumps potassium into the cell and sodium out in a ratio of 3:2.

    The second was the cotransporter which he glossed over. I know that this cotransporter takes chloride out and puts potassium in. But can someone explain to me how this cotransporter works, and whether sodium is involved ?

  2. jcsd
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