Buzz Bloom
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Hi Vladimir:Vladimir Matveev said:The protein matrix of a protocell similar to Fox's microspheres can adsorb amino acids from the environment non-randomly again.
The Wikipedia summary of Sydney Fox's experiment says that proteins were never produced.
https://en.wikipedia.org/wiki/Sidney_W._Fox
One of the first experiments by Dr. Fox and Kaoru Harada that had to do with the formation of proteinoids was called Thermal Copolymerization of Amino Acids to a Product Resembling Protein. It was performed in February 1958.
The experiment did not prove that proteins were formed on primordial Earth using primarily heat, but Fox and Kaoru Harada believed it suggested that if proteinoids could be synthesized using just heat and the amino acids formed from the Miller–Urey experiment, then more research could lead to an answer to how anabolic reactions, enzymatic proteins, and nucleic acids were first formed and in turn, how the earliest forms of life originated.
AFAIK, proteinoids have never been demonstrated to have any useful enzymatic properties.One of the first experiments by Dr. Fox and Kaoru Harada that had to do with the formation of proteinoids was called Thermal Copolymerization of Amino Acids to a Product Resembling Protein. It was performed in February 1958.
The experiment did not prove that proteins were formed on primordial Earth using primarily heat, but Fox and Kaoru Harada believed it suggested that if proteinoids could be synthesized using just heat and the amino acids formed from the Miller–Urey experiment, then more research could lead to an answer to how anabolic reactions, enzymatic proteins, and nucleic acids were first formed and in turn, how the earliest forms of life originated.
Also AFAIK no scenario has ever been proposed for how hypothetical proteinoids with enzymatic properties could improve by mutation. In contrast, RNA sequences do mutate when reproducing, and RNA ribozymes have been demonstrated to have enzymatic properties.
Regards,
Buzz