Given an [itex]x_1,x_2, ..., x_n[/itex] Cartesian coordinate system, the the equation of the n-sphere of radius R, with center at the origin is [itex]x_1^2+ x_2^2+ x_3^2+ \cdot\cdot\cdot+ x_n^2= R^2[/itex].
It is clear that, if all the other variables are 0, then [itex]x_1^2= R^2[/itex] so that [itex]x_1[/itex] ranges between -R and R to cover the entire n-sphere. In the [itex]x_1x_2[/itex] plane, all other variables 0, [itex]x_1^2+ x_2^2= R^2[/itex] so that, for fixed [itex]x_1[/itex], [itex]x_2= \pm\sqrt{R^2- x_1^2}[/itex] and so [itex]x_2[/itex] ranges between [itex]-\sqrt{R^2- x_1^2}[/itex] and [itex]\sqrt{R^2- x_1^2}[/itex] etc.
Continuing like that, we see that the volume is given by
[tex]\int_{-R}^R\int_{-\sqrt{R^2- x_1^2}}^{\sqrt{R^2- x_1^2}}\int_{-\sqrt{R^2- x_1^2- x_2^2}}^{\sqrt{R^2- x_1^2- x_2^2}}\cdot\cdot\cdot\int_{-\sqrt{R^2- x_1^2- x_2^2- \cdot\cdot\cdot- x_{n-1}^2}}^{\sqrt{R^2- x_1^2- x_2^2- \cdot\cdot\cdot- x_{n-1}^2}} dx_ndx_{n-1}\cdot\cdot\cdot dx_2 dx_1[/tex].
You ought to be able to take the formulas for area of a circle (2-sphere), volume of a sphere (3-sphere) and use that integral to find the hyper-volumes of the 4-sphere, 5-sphere, etc to find a general formula.