Particle accelerators face significant physical limitations that prevent them from being miniaturized to just a few centimeters while achieving performance surpassing the Large Hadron Collider (LHC). The strength of electric fields necessary for acceleration is constrained, requiring longer distances for effective acceleration due to the small charge of particles. Additionally, synchrotron radiation becomes a major issue in smaller accelerators, as increased centripetal acceleration leads to greater energy loss. While plasma wakefield acceleration offers potential for higher gradients, it struggles with beam quality, making it unsuitable for collision science. Future advancements may allow for longer accelerators in space, where fewer materials are needed, but significant challenges remain in achieving compact, high-energy systems.