What are the two types of ATP synthesis and how do they differ?

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The discussion clarifies the two types of ATP synthesis: direct ATP synthesis, known as substrate-level phosphorylation, and indirect ATP synthesis, referred to as oxidative phosphorylation. Substrate-level phosphorylation involves a molecule directly donating a phosphate group to ADP, while oxidative phosphorylation occurs in the electron transport chain, utilizing the proton motive force (PMF) to attach inorganic phosphate to ADP. Key examples include the conversion of succinyl CoA to succinic acid in the Krebs cycle, which illustrates the energy transfer involved in these processes.

PREREQUISITES
  • Understanding of ATP synthesis mechanisms
  • Familiarity with substrate-level phosphorylation
  • Knowledge of oxidative phosphorylation
  • Basic concepts of the electron transport chain
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gracy
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I came across a term "indirect atp formation"I am not sure what it is ?
What is the difference between direct and indirect atp synthesis?I think substrate level phosphorylation (where a molecule directly donates a phosphate to ADP) is direct atp synthesis.Indirect atp synthesis is oxidative phosphorylation (in the electron transport chain; using the H+ gradient to attach inorganic phosphate to ADP).
Right?
 
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gracy said:
think substrate level phosphorylation (where a molecule directly donates a phosphate to ADP) is direct atp synthesis
The phosphate need not come from the molecule, the energy liberated during the conversion might just help in adding that Pi to ADP/GDP, eg:succinyl CoA to succinic acid in kreb's cycle.
gracy said:
oxidative phosphorylation (in the electron transport chain; using the H+ gradient to attach inorganic phosphate to ADP).
Yes, by PMF(proton motive force) and oxysomes(FoF1 particle)
 

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