What Is the Correct Sequence of Protein Processing in Cells?

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The correct sequence of protein processing in cells begins with the synthesis of a membrane protein in the rough endoplasmic reticulum. Next, the unmodified protein is transported to a vesicle membrane. The protein then undergoes glycosylation, becoming a glycoprotein. Following this, the glycoprotein is modified further before being integrated into the plasma membrane with the sugar modification facing outside the cell. This sequence highlights the essential steps in protein processing and transport within cellular structures.
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Homework Statement



Consider the following events:

1) The protein has sugar added to become a glycoprotein.

2) The protein is in the plasma membrane with the sugar modification facing outside the cell.

3) A membrane protein is synthesized in the rough endoplasmic reticulum.

4) The glycoprotein is present in the membrane of a vesicle.

5) The sugars on the glycoprotein are modified.

6) The unmodified protein is present in the membrane of a vesicle.

What is the correct order of the events?



Homework Equations



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The Attempt at a Solution



3) A membrane protein is synthesized in the rough endoplasmic reticulum.
6) The unmodified protein is present in the membrane of a vesicle.
1) The protein has sugar added to become a glycoprotein.
4) The glycoprotein is present in the membrane of a vesicle.
5) The sugars on the glycoprotein are modified.
2) The protein is in the plasma membrane with the sugar modification facing outside the cell.
 
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I agree. But then again it doesn't appear to offer much choice anyway.
 

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