I do not think your question as stated is very understandable.
The first thing I don't understand is what you mean by "invalidate an experiment" ?
An experiment which has been correctly done is merely an observation of Nature and can not be invalidated, unless it has been done wrongly.
http://wordnet.princeton.edu/perl/webwn?s=valid
well grounded in logic or truth or having legal force, or still legally acceptable
You can invalidate an interpretation, but not an experiment.