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- TL;DR Summary
- What events trigger fatigue during an illness and how?
What is the mechanism of Fatigue what events initiate it and how?
[CODE title="The wikipedia definition of Fever"]The trigger of a fever, called a pyrogen, results in the release of prostaglandin E2 (PGE2)[/CODE]
Generally just as a pyrogen such as PGE2 (or LPS) sets thermogenesis in motion, leading to a fever, what kind of events are triggered in physical and mental fatigue during an illness?
I want to know the basic pathophysiology or the sequence of events that are triggered to cause fatigue or tiredness during an illness.
Thanks in advance,
[CODE title="The wikipedia definition of Fever"]The trigger of a fever, called a pyrogen, results in the release of prostaglandin E2 (PGE2)[/CODE]
Generally just as a pyrogen such as PGE2 (or LPS) sets thermogenesis in motion, leading to a fever, what kind of events are triggered in physical and mental fatigue during an illness?
I want to know the basic pathophysiology or the sequence of events that are triggered to cause fatigue or tiredness during an illness.
Thanks in advance,