A non-inertial frame is defined by its acceleration, which is invariant and can be measured using an accelerometer without reference to any other frame. Proper acceleration is not relative to any frame, and it is essential for defining inertial frames, which are characterized by having zero proper acceleration for stationary objects. The discussion emphasizes that while kinematic quantities are often frame-dependent, proper acceleration remains invariant across different inertial frames. The concept of proper acceleration is compatible with classical mechanics, although it may not be explicitly mentioned in introductory texts. Overall, the distinction between proper acceleration and coordinate acceleration is crucial for understanding motion in both inertial and non-inertial frames.