Why do acidic drugs remain unionized in acidic environement?

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Discussion Overview

The discussion revolves around the behavior of acidic and basic drugs in different pH environments, specifically why acidic drugs remain unionized in acidic environments and become ionized in basic environments, while the opposite is true for basic drugs. The scope includes concepts from chemistry related to acid/base equilibrium.

Discussion Character

  • Conceptual clarification
  • Debate/contested

Main Points Raised

  • One participant asks why acidic drugs remain unionized in acidic environments and become ionized in basic environments, and similarly for basic drugs.
  • Another participant suggests that the question is basic and refers to the behavior of acids and bases, implying that understanding acid/base equilibrium is essential.
  • A third participant humorously misinterprets the term "unionized," indicating a playful take on the subject matter.
  • A later reply reiterates the basic nature of the question and emphasizes the need for knowledge in acid/base equilibrium, while also correcting the thread's category from medical sciences to chemistry.

Areas of Agreement / Disagreement

Participants do not reach a consensus on the explanation of the behavior of drugs in different pH environments, and the discussion includes both serious inquiries and humorous interpretations.

Contextual Notes

Some participants express assumptions about the foundational knowledge required to understand the topic, indicating a potential gap in understanding acid/base equilibrium among some readers.

tarekatpf
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Why do acidic drugs remain unionized in acidic environement, and become ionized in basic environment?

Similarly, why do basic drugs become ionized in acidic environment and remain unionized in basic environment?
 
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This is a pretty basic question about behavior of acids and bases. Short answer: because that's exactly the way they behave. Long answer: please learn about acid/base equilibrium, this is part of GenChem101.

Actually this is a chemistry question, not medical sciences. I am moving the thread.
 
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When I read the subject, I thought you were asking about why acidic drugs were involved in collective bargaining :smile:
 
phinds said:
When I read the subject, I thought you were asking about why acidic drugs were involved in collective bargaining :smile:

That's how you know if someone is a Chemist or not. You ask them to pronounce unionized.

Un-ionized = Chemist
Union-ized = Not a Chemist

:smile:
 
Borek said:
This is a pretty basic question about behavior of acids and bases. Short answer: because that's exactly the way they behave. Long answer: please learn about acid/base equilibrium, this is part of GenChem101.

Actually this is a chemistry question, not medical sciences. I am moving the thread.

Thank you very much for your suggestion and correcting the category. And sorry about my late reply as I have been sick lately.
 

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