Why Do I Get Tired After Eating A Lot?

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Discussion Overview

The discussion revolves around the reasons for feeling tired after consuming a large meal, exploring various physiological mechanisms, including insulin response, blood glucose levels, and the effects of certain nutrients on brain chemistry. The scope includes theoretical explanations and physiological responses related to digestion and energy levels.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested

Main Points Raised

  • Some participants propose that the body expends energy in breaking down food, leading to fatigue.
  • Others argue that insulin and blood sugar levels play a significant role, suggesting that high blood glucose can deactivate orexin neurons, which are responsible for alertness.
  • One participant mentions that low blood sugar levels, resulting from an overproduction of insulin, may cause post-meal drowsiness, referred to as "food coma."
  • Another viewpoint highlights the role of tryptophan and serotonin production in the brain after consuming foods high in sugar and carbohydrates, suggesting a biochemical pathway that contributes to sleepiness.
  • There is a question regarding whether insulin's effect on amino acid uptake pertains to muscle cells or general cellular uptake for protein synthesis.
  • A later reply discusses the context of sugar consumption by athletes, noting that sugar can be beneficial during exercise without the same drowsiness effects experienced after a meal.

Areas of Agreement / Disagreement

Participants express multiple competing views regarding the causes of post-meal fatigue, with no consensus reached on a singular explanation. The discussion remains unresolved with various hypotheses presented.

Contextual Notes

Some claims depend on specific definitions of terms like "food coma" and "postprandial somnolence," and the discussion includes references to biochemical processes that may not be fully agreed upon.

JerryClower
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My theory is that my body is putting more energy into breaking down foods and converting the food into energy my body can use. What do you think is the reason for this?
 
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It has more to do with insulin, and blood sugars. High blood glucose levels, can switch off the brain cells{orexin neurons} that normally keep us awake and alert.
I believe it occurs in all mammals.
 
hypatia said:
It has more to do with insulin, and blood sugars. High blood glucose levels, can switch off the brain cells{orexin neurons} that normally keep us awake and alert.
I believe it occurs in all mammals.
Eat thanksgiving meal, get dozy. It's probably a good thing that male African lions always feed first. They get fat and dozy and forget to kill the cubs.
 
I've heard that it is low glucose levels, not high ones that are responsible. After we eat, our blood glucose levels are elevated causing the release of insulin. Sometimes, if the blood glucose levels are high enough, the body will overcompensate with the insulin resulting in a period of low blood sugar after the insulin has done its work. It's this low glucose period that causes the "food coma."
 
The fancy name is "Postprandial somnolence". What happens is that when you eat food high in sugar and carbohydrates (which are converted into sugar), your blood glucose levels rise. This causes the body to respond with insulin production, which takes the sugar and amino acids out of your blood.

What happens is that insulin does not have an effect on the amino acid tryptophan, which relative levels in the blood will rise. This causes the neural amino acid transport to shift to transport of tryptophan to the brain, the brain responds in making serotonin (causing the happy feeling), which can be metabolized into melatonin (which regulates circadian rhythm).

Article http://wurtmanlab.mit.edu/publications/pdf/178.pdf"
 
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Monique when you say insulin increases amino acid uptake, are you talking about muscle cells where gluconeogenesis can not occur?
 
Monique said:
The fancy name is "Postprandial somnolence". What happens is that when you eat food high in sugar and carbohydrates (which are converted into sugar), your blood glucose levels rise. This causes the body to respond with insulin production, which takes the sugar and amino acids out of your blood.

What happens is that insulin does not have an effect on the amino acid tryptophan, which relative levels in the blood will rise. This causes the neural amino acid transport to shift to transport of tryptophan to the brain, the brain responds in making serotonin (causing the happy feeling), which can be metabolized into melatonin (which regulates circadian rhythm).

Article http://wurtmanlab.mit.edu/publications/pdf/178.pdf"

So eating sugar actually makes one feel sleepy rather than giving a "boost up"?
Don't sportsmen eat sugar while in a prolonged effort? Before a marathon I can understand eating carbohydrate that will later be converted in sugar... but during the run, eating (or drinking) sugar will actually makes the runner sleepy? I just want to be sure I'm not misunderstanding.
 
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  • #10
I realize that this is very late but I'll post the answer anyway...

When sportsmen consume sugar during exercise the system is able to absorb the sugar without the need to balance it. This is because there is a need for it. They will take it during or post exercise only and never pre because before exercise insulin is produced by the body which reacts in the way outlined above (removing many amino acids allowing tryptophan to predominate and later causing melatonin in the brain) and also other unwanted effects.
 

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