Why do you get pressure drop in central circulation?

Click For Summary

Discussion Overview

The discussion centers on the reasons for pressure drops in the central circulation, particularly the transition from arteries to arterioles. Participants explore the implications of vessel radius, surface area, and resistance in this context.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested

Main Points Raised

  • One participant notes that the transition from arteries to arterioles involves many branches, leading to an increase in total radius, which could suggest a decrease in resistance.
  • Another participant introduces the concept of viscosity and surface area, arguing that smaller ducts have more surface area for friction, which complicates the relationship between radius and resistance.
  • A subsequent reply acknowledges the decrease in resistance due to increased radius but suggests that the larger surface area in arterioles leads to increased friction, which may outweigh the decrease in resistance.
  • Further clarification is sought regarding the relationship between radius, area, and pressure drop, with one participant expressing confusion over the implications of increased radius on pressure.
  • Another participant reiterates the idea that increased surface area contributes to increased resistance, leading to a significant pressure drop despite the larger radius.
  • A request for confirmation of these ideas is made, indicating uncertainty about the correctness of the claims presented.

Areas of Agreement / Disagreement

Participants express differing views on how the increase in surface area and radius affects resistance and pressure drop, indicating that the discussion remains unresolved with multiple competing perspectives.

Contextual Notes

Participants reference concepts such as laminar flow and Poiseuille flow, but there is no consensus on how these concepts apply to the pressure drop in the transition from arteries to arterioles.

Joojo
Messages
4
Reaction score
0
What is the reason that the pressure drops in the central circulation?especially if you go from arteries to arterioles you get a huge pressure drop.

If you look what is changing if you go from arteries to arterioles then it is that you get many many branches this leads to an increase of total radius.(the individual radii of the arterioles are smaller but the sum of them all is larger than aorta/arteries). So because of this increase in total radius you could say that the resistance should drop. So if the resistance is dropping(in stead of increasing) how is it that you get this huge pressure drop?
 
Biology news on Phys.org
Hello Joojo, :welcome:

Has to do with viscosity and the fact that 1000 small ducts have a lot more nearby surface to stick to than one big one with the same area. In the big duct there is e.g. a 0.1 mm 'boundary layer' between velocity zero at the wall and the plug flowing bulk. In a 0.2 mm arteriole it is all boundary layer.

cf resistance to flow in Poiseuille flow
Here they even have blood flow examples

The radius dependence is very strong for laminar flow; with bigger ducts there will be plug flow, perhaps even some turbulence and then the dependence is less drastic.
 
Last edited:
  • Like
Likes   Reactions: Joojo
Thank you. Never thought about it from that perspective.
So what you are saying is that the increase in radius does decrease the resistance(even thoug it is not as big a factor as in the arterial system, becouse the flow in the arterioles is not laminar). But at the same time you have a much bigger area([PLAIN]http://www.mathgoodies.com/lessons/vol2/images/area_formula.gif) and this area is cousing for a much bigger friction which increases the resistance.
And this increase in resistant(from the increased area) is much bigger than the decrease of resistance(from the bigger radius) so overal the resistance increases and this leads to that big pressure drop?
 
Last edited by a moderator:
You have lost me somewhat. Perhaps because I am unfamiliar with the medical terms. Increase in radius decreases resistance, yes. Bigger area (cross section area) means less pressure drop.

The part 'at the same time' eludes me completely. It seems you now expect a pressure drop when the radius increases ?

In post #1: "from arteries to arterioles you get a huge pressure drop". I interpreted that as: the pressure in the bigger ducts is higher than in the narrower ones. Is that what you meant ?
 
BvU said:
In post #1: "from arteries to arterioles you get a huge pressure drop". I interpreted that as: the pressure in the bigger ducts is higher than in the narrower ones. Is that what you meant ?
Yes that is what i meant.
BvU said:
You have lost me somewhat. Perhaps because I am unfamiliar with the medical terms. Increase in radius decreases resistance, yes. Bigger area (cross section area) means less pressure drop.

With the area i mean because al those vessels now have much more surface area for friction so this will lead to increase resistance and this increase resistance should lead to a big pressure drop.

And even though the increased radius should have caused and decrease in resistance and thereby pressure difference should decrease, this is not going to happen because the increased resistance by way of the increased friction(due to increased area for friction to happen)is playing a much bigger role. So overall the resistance in increasing in the arterioles and this leads to that big pressure drop.
 
Can anybody confirm this please?:oldconfused:
 

Similar threads

  • · Replies 3 ·
Replies
3
Views
2K
  • · Replies 10 ·
Replies
10
Views
3K
  • · Replies 7 ·
Replies
7
Views
9K
  • · Replies 2 ·
Replies
2
Views
14K
Replies
3
Views
4K
  • · Replies 2 ·
Replies
2
Views
11K
  • · Replies 7 ·
Replies
7
Views
2K
  • · Replies 29 ·
Replies
29
Views
10K
  • · Replies 8 ·
Replies
8
Views
3K
Replies
1
Views
5K