Why does the penis stop responding to testosterone after puberty?

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SUMMARY

The discussion centers on the ineffectiveness of penis enlargement procedures and the lack of hormonal treatments to increase penis size in adults post-puberty. Participants explore the biochemical reasons behind the diminished responsiveness of penile tissue to testosterone after puberty. It is established that current medical technology has not yet developed a method to replicate the hormonal environment of puberty in adults, despite significant demand for such solutions.

PREREQUISITES
  • Understanding of testosterone's role in male development
  • Basic knowledge of human reproductive anatomy
  • Familiarity with hormonal signaling and receptor function
  • Awareness of current medical procedures for penis enlargement
NEXT STEPS
  • Research the biochemical mechanisms of testosterone receptor desensitization
  • Investigate current advancements in hormonal therapies for adult males
  • Explore the effectiveness and risks of existing penis enlargement surgeries
  • Learn about the role of growth factors in tissue expansion and regeneration
USEFUL FOR

This discussion is beneficial for medical professionals, endocrinologists, and individuals interested in male reproductive health and the science behind penis enlargement treatments.

jaumzaum
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Penis enlargement procedures/surgeries are not that effective yet. I was wondering why there isn't any hormonal treatment that increases penis size in adults after puberty. Why the receptors in our penis tissue stop responding so well to testosterone after puberty? Biochemistrily speaking, why can't we simulate the puberty hormonal environment in an adult, even a little, and get a measurable penis growth? I find it very weird that with our current medical technology this is not yet possible, although there is a very high demand for it.
 
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