Of course, it would be (mathematically) possible to have something like [itex]F= C_1mz+ C_2a[/itex] where [itex]C_1[/itex] and [itex]C_2[/itex] are constants with the correct units ([itex]C_1[/itex] would have to have units of "Newtons per kg" or "meters per second squared" and [itex]C_2[/itex] has units of "Newtons-seconds square per meter" or "kilograms".
But the only good Physics explanation as to why a specific formula is true is "that is what the experimental evidence shows".