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Why is Benadryl used to counter the dysphoric effects of Haldol

  1. Jul 16, 2017 #1

    berkeman

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    Staff: Mentor

    I was reading a paramedic article about pre-hospital treatment of agitated patients before or during transport to the hospital. They mention that Haldol or benzodiazepines can be effective for this (consult your local Medical Director, of course), and that it is often given in combination with Benadryl (diphenhydramine) to counter the dysphoric effects (a feeling of unease or emotional distress) of Haldol in some people.

    In reading about Benadryl, I haven't seen this effect addressed or explained. Does anybody know the physiology behind this action of Benadryl?
     
  2. jcsd
  3. Jul 16, 2017 #2

    OCR

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    Last edited: Jul 16, 2017
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