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Serenie
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The topic in the prize is about GPCR and from what i have researched, the research is about biology. I want to know why it was rewarded to the field in chemistry.
Probably because they were working at the chemistry level with methods methods that were as much chemistry as physilogy or medicine.Serenie said:The topic in the prize is about GPCR and from what i have researched, the research is about biology. I want to know why it was rewarded to the field in chemistry.
Lefkowitz started to use radioactivity in 1968 in order to trace cells' receptors. He attached an iodine isotope to various hormones, and thanks to the radiation, he managed to unveil several receptors, among those a receptor for adrenalin: β-adrenergic receptor. His team of researchers extracted the receptor from its hiding place in the cell wall and gained an initial understanding of how it works.
The Nobel Prize in Physiology or Medicine 2012 was awarded jointly to Sir John B. Gurdon and Shinya Yamanaka "for the discovery that mature cells can be reprogrammed to become pluripotent"
The Nobel Prize in Chemistry 2012 was awarded jointly to Robert J. Lefkowitz and Brian K. Kobilka "for studies of G-protein-coupled receptors".
G-protein-coupled receptors are a type of protein found on the surface of cells that play a crucial role in cell communication and the regulation of various physiological functions.
Lefkowitz and Kobilka were awarded the Nobel Prize for their groundbreaking work in studying the structure and function of G-protein-coupled receptors, which has greatly advanced our understanding of how these receptors work and their importance in various biological processes.
Their research has had a significant impact on the field of chemistry and biology, as it has provided valuable insights into the structure and function of G-protein-coupled receptors, which are important targets for drug development and play a critical role in various diseases and disorders.
The Nobel Prize in Chemistry is awarded annually by the Royal Swedish Academy of Sciences to individuals or groups who have made outstanding contributions to the field of chemistry. The nominations and selection process for the prize involves a rigorous evaluation by a committee of experts in the field.