Discussion Overview
The discussion centers around the best computational methods for calculating solvent accessible surface area, particularly in the context of protein folding and protein-ligand docking.
Discussion Character
- Exploratory, Technical explanation
Main Points Raised
- One participant inquires about efficient methods for calculating solvent accessible surface area in specific biological phenomena.
- Another participant mentions Midas and MidasPlus as potential tools, suggesting that the code might still be accessible for review.
- A subsequent reply questions the current relevance of MidasPlus, noting that it has been replaced by Chimera.
- There is a request for the location of the code related to Midas and MidasPlus.
Areas of Agreement / Disagreement
Participants do not appear to reach a consensus on the best method, and there are competing views regarding the relevance of MidasPlus versus Chimera.
Contextual Notes
There are references to specific software tools and their historical context, but the discussion does not clarify the current capabilities or limitations of these tools in relation to the inquiry.