Biochemical reason behind (neurotic) perfectionism

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SUMMARY

The biochemical basis of neurotic perfectionism is closely linked to Obsessive-Compulsive Disorder (OCD) and Obsessive-Compulsive Personality Disorder (OCPD). The DSM-V defines perfectionism as a characteristic of OCD, highlighting the relationship between these disorders. While the underlying mechanisms remain largely unexplored, resources from the National Institute of Mental Health (NIMH) provide valuable insights into the biochemistry of OCD. Notably, neurotic perfectionism is often a manifestation of OCPD, which is distinct from OCD but frequently comorbid with it.

PREREQUISITES
  • Understanding of DSM-V classifications, particularly regarding OCD and OCPD.
  • Familiarity with biochemical research methods related to mental health disorders.
  • Knowledge of the physiological differences in brain function associated with OCD.
  • Access to academic resources such as NIMH and PubMed for in-depth research.
NEXT STEPS
  • Research the biochemical mechanisms of OCD through NIMH resources.
  • Study the physiological differences in the brains of OCD patients via relevant academic papers.
  • Explore the distinctions between OCD and OCPD in clinical psychology literature.
  • Investigate the comorbidity of OCPD with other disorders, including eating disorders.
USEFUL FOR

Mental health professionals, psychologists, and researchers interested in the biochemical and psychological aspects of perfectionism and its relationship with OCD and OCPD.

Tyto alba
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Is the reason behind neurotic perfectionism known? I'm looking for the molecular basis of this kind of perfectionism but couldn't find much on Google - Web and Scholar.
 
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Try googling to OCD - obsessive-compulsive disorder. And I do not know if there is any really complete biochemical explanation. NIMH is where you want to go for any known answers.

Google NIMH: OCD biochemistry and you get lots of hits. All with valid information.
Here is one:
https://www.ncbi.nlm.nih.gov/pubmed/17679639

I get the idea that you are really trying to answer some other question, not the one you stated.
 
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No, I'm trying to find an answer to the question I stated.

Does a case of (neurotic) perfectionism necessarily have to be one of OCD?
 
The DSM-V defines perfectionism as an aspect of obsessive-compulsive disorder. Whilst the DSM is obviously subject to change it represents that the current consensus is that the two are related.
http://www.psi.uba.ar/academica/carrerasdegrado/psicologia/sitios_catedras/practicas_profesionales/820_clinica_tr_personalidad_psicosis/material/dsm.pdf

As with most mental health disorders the underlying mechanism is not completely understood, especially at a biochemical level. The paper suggested by Jim is a good start for you as it looks into some of the physiological differences within the brains of OCD patients.
 
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"Neurotic perfectionism," as phrased, would actually be a manifestation of Obsessive-Compulsive Personality Disorder, which is a disorder distinct from Obsessive-Compulsive Disorder.

https://en.wikipedia.org/wiki/Obsessive–compulsive_personality_disorder

Confusion arises because of the similar names and because many with one disorder also have the other: they are often comorbid.

OCPD is often confused with obsessive–compulsive disorder (OCD). Despite the similar names, they are two distinct disorders—OCD is an anxiety disorder and OCPD is a personality disorder. Some OCPD individuals do have OCD, and the two are sometimes found in the same family,[14] sometimes along with eating disorders.[15] People with OCPD do not generally feel the need to repeatedly perform ritualistic actions—a common symptom of OCD—and usually find pleasure in perfecting a task, whereas people with OCD are often more distressed after their actions...

That said, the cause of both is still unknown.
 
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