Breakthrough Prize: Genome Editing with CRISPR-Cas9

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SUMMARY

The forum discussion centers on the groundbreaking advancements in genome editing using CRISPR-Cas9 technology. Researchers have successfully engineered molecules capable of precisely cutting DNA within microbes and human cells, allowing for targeted genetic modifications. Notably, Motoko Araki and Tetsuya Ishii from Hokkaido University predict imminent applications of CRISPR for altering human embryos. MIT Technology Review has recognized CRISPR as the most significant biotech discovery of the century, highlighting its potential to revolutionize medicine.

PREREQUISITES
  • Understanding of CRISPR-Cas9 technology
  • Familiarity with molecular biology concepts
  • Knowledge of genetic engineering techniques
  • Awareness of ethical considerations in gene editing
NEXT STEPS
  • Research the latest advancements in CRISPR-Cas9 applications in human gene therapy
  • Explore the ethical implications of gene editing in human embryos
  • Learn about alternative genome editing tools like TALENs and ZFNs
  • Investigate the regulatory landscape surrounding CRISPR technology
USEFUL FOR

This discussion is beneficial for geneticists, molecular biologists, bioethicists, and anyone involved in biotechnology and gene therapy research.

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They crafted molecules that could enter a microbe and precisely snip its DNA at a location of the researchers’ choosing.

In January 2013, the scientists went one step further: They cut out a particular piece of DNA in human cells and replaced it with another one.

Writing last year in the journal Reproductive Biology and Endocrinology, Motoko Araki and Tetsuya Ishii of Hokkaido University in Japan predicted that doctors will be able to use CRISPR to alter the genes of human embryos "in the immediate future."

Thanks to the speed of CRISPR research, the accolades have come quickly. Last year MIT Technology Review called CRISPR "the biggest biotech discovery of the century."

http://www.businessinsider.com/the-...-about-to-change-medicine-forever-2015-2?IR=T

 
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Biology news on Phys.org
Interesting, this looks quite promising for gene-modified cell therapy if it can be shown to work as well as advertised.
 
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What are these molecular scissors that the narrator talks about?
 

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