Can the Fine Structure Constant Be Calculated from First Principles?

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The discussion centers on the challenge of calculating the fine structure constant from first principles, as highlighted by Griffiths's QM textbook. It notes that despite attempts by prominent scientists like Sir Arthur Eddington, no definitive axioms exist for this endeavor, which transcends the standard model of physics. Most research in this area is conducted within the framework of string theory, which may eventually provide a mathematical proof for the fine structure constant's necessity and universality. The conversation emphasizes the complexity and significance of this problem in theoretical physics. Ultimately, the quest for a foundational understanding of the fine structure constant remains open and unresolved.
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Griffiths's QM textbook says on page 236 regarding the fine structure constant calculation from first principles:

"If you can solve part (b), you have the most certain Nobel Prize in history waiting for you".

Just for curiosity, since I'm aware that giants like Sir Arthur Eddington tried and failed, what are the axioms to start such a quest?
 
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There is no definite set of axioms from which to start, since such a questsion goes beyond the standard model. Most work beyond the standard model is done in string theory, and in principle this framework could contain a mathematical proof of why the value of the fine structure constant is necessary and universal.
 
Insights auto threads is broken atm, so I'm manually creating these for new Insight articles. Towards the end of the first lecture for the Qiskit Global Summer School 2025, Foundations of Quantum Mechanics, Olivia Lanes (Global Lead, Content and Education IBM) stated... Source: https://www.physicsforums.com/insights/quantum-entanglement-is-a-kinematic-fact-not-a-dynamical-effect/ by @RUTA

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