Can transgene be made dominant?

[anubodh]

Can we make transgene dominant in the genetically engineered organism so that when it mates the offspring would have the same characteristics?

 

[arunshanker]

Yes by insertion of the transgene in the germ cell

 

[Ygggdrasil]

Whether an allele of a gene acts in a dominant or recessive manner depends on the biochemistry of how the allele functions. In general, most loss-of-function alleles act in a recessive manner and most gain-of-function allele act in a dominant manner. Of course, there are many exceptions, such as dominant negative alleles which can interfere with the function of the wild type allele.

Here's a previous PF thread on the topic:
https://www.physicsforums.com/showthread.php?t=568436

And here's a useful article on the subject:
http://genetics.thetech.org/ask/ask227