Catabolism exergonic yet breaking a bond is endothermic?

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SUMMARY

Catabolic reactions in biology are exergonic, meaning they release energy, while breaking chemical bonds is endothermic, requiring energy input. This distinction arises because biological catabolism often involves the formation of new bonds, such as CO2 and H2O, which release more energy than is consumed in breaking the original bonds. The relationship between these concepts is clarified by understanding that energy changes in biological systems are influenced by the overall reaction, not just individual bond breaking or forming. Anabolic processes are endergonic, yet the formation of certain bonds can be exothermic, highlighting the complexity of energy dynamics in biochemical reactions.

PREREQUISITES
  • Understanding of basic biological concepts, specifically catabolism and anabolism.
  • Familiarity with thermodynamics, particularly exergonic and endergonic reactions.
  • Knowledge of chemical bonding and bond energy principles.
  • Awareness of metabolic pathways and their energy implications.
NEXT STEPS
  • Research the Gibbs free energy equation and its application in biological reactions.
  • Study the differences between catabolic and anabolic pathways in cellular metabolism.
  • Explore the concept of bond energies and how they relate to reaction spontaneity.
  • Investigate specific examples of metabolic reactions that illustrate these principles, such as cellular respiration.
USEFUL FOR

Students of biology, biochemistry enthusiasts, educators teaching metabolic processes, and anyone interested in the energy dynamics of biochemical reactions.

ngu9997
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Hi - really basic question here, but I was wondering. In biology it's said that catabolic reactions which break something down release energy, making such exergonic. In chemistry it is said that breaking bonds is endo-thermic. This seems counter-intuitive to me? But, I realize it's because the two concepts are different yet related by a formula? Could someone explain to me why it's not actually counter-intuitive and where my line of reasoning is wrong?Also I guess this question would also work talking about why anabolism is endergonic, yet forming bonds is exothermic.
 
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In chemistry you rarely break a bond without forming new ones. "Breaking something down" in biology usually means forming more water and CO2, or other HO and CO bonds, and forming these tends to release a lot of energy compared to CC, CH and OO bonds (e. g. hydrocarbons and oxygen).
 

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