Cell division and chromosome errors

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SUMMARY

Cell division processes, specifically mitosis, ensure that daughter cells inherit identical genetic material from the parent cell, maintaining the same order and number of genes on chromosomes. During meiosis, however, homologous chromosomes undergo approximately 40 cross-overs, leading to genetic variation. Chromosomal rearrangements, such as translocations, primarily occur in response to double strand breaks, which are more prevalent in regions with long CG sequences. Enzymes play a crucial role in mediating gene exchange during these crossovers.

PREREQUISITES
  • Understanding of mitosis and meiosis processes
  • Knowledge of chromosomal structure and function
  • Familiarity with double strand breaks and their implications
  • Basic concepts of genetic recombination and crossover mechanisms
NEXT STEPS
  • Research the mechanisms of mitosis and meiosis in detail
  • Study the role of enzymes in genetic recombination during meiosis
  • Explore the significance of double strand breaks in chromosomal stability
  • Investigate the impact of CG-rich sequences on chromosomal integrity
USEFUL FOR

Students and professionals in genetics, molecular biology researchers, and educators looking to deepen their understanding of cell division and chromosomal behavior.

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What changes would have to be made to a cell
so that when it divides the genes in the daughter cells
are exactly the same,in the same order and number on the chromosomes,
as they were in the parent cell?
 
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What are you implying that happens otherwise during mitosis?

The daughter cells are always the same, only during meiosis do you get about 40 cross-overs, that occur due that the fact that homologous chromosomes are alligned next to each other.

I don't think that any rearranging takes place during mitosis, only in cells that have double strand breaks will you start seeing chromosomal translocations.
 
Strands are more likely to break where there is a long CG sequence e.g.
CG CG CG CG CG CG CG.Why is this?
Also when crossovers occur are enzymes needed to mediate exchange of
genes?
 
Last edited:

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