Assuming that we have a chemical plant which produces methanol through the following equations: CH4 + H2O <--> CO + 3H2 CO + 2H2 <--> CH3OH CO2 + 3H2 <--> CH3OH + H2O I know that with specific pressure, temperature and flow rates, I can produce reactions with specific equilibrium constants. Are these conditions maintained until water and methanol are separated, even in the pipelines? I'm guessing that I can calculate the theoretical yield by applying the equilibrium constant. Is that correct? Thank you for your time. Edit: Also, wouldn't I risk changing the position of equilibrium if I change the conditions to separate water and methanol?