Could you gain A LOT of weight by drinking LOTS of deuterium water?

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Discussion Overview

The discussion revolves around the potential effects of consuming large amounts of deuterium oxide (D2O) on body weight and health. Participants explore the implications of replacing regular water (H2O) with heavy water (D2O) over an extended period, considering both the physical and biochemical consequences.

Discussion Character

  • Exploratory
  • Technical explanation
  • Conceptual clarification
  • Debate/contested

Main Points Raised

  • Some participants suggest that significant weight gain could occur due to the replacement of H2O with D2O, although the timeframe for complete replacement is uncertain.
  • Concerns are raised about potential health risks associated with increased viscosity and altered properties of blood and body fluids, which could impair organ function.
  • One participant calculates that replacing H2O with D2O would add approximately 11% to the water weight, questioning whether this constitutes "A LOT."
  • There are claims that diffusion rates, chemical reaction rates, and evaporation processes may be negatively affected by the presence of D2O.
  • Another participant mentions that while the permeability of water and D2O through aquaporin-1 is similar, the replacement of hydrogen with deuterium in proteins could alter their activities, although they note a lack of clear studies on this.
  • One participant speculates that the isotopic effect of deuterium may disrupt the dynamic equilibrium within cells, leading to imbalances in concentrations of various substances.

Areas of Agreement / Disagreement

Participants express a range of views on the implications of consuming D2O, with some agreeing on the potential for health risks while others focus on the physical weight gain aspect. The discussion remains unresolved regarding the extent and nature of these effects.

Contextual Notes

Limitations include assumptions about the timeframe for complete replacement of body water and the specific health risks associated with D2O consumption, which are not fully explored or quantified in the discussion.

Simfish
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You could gain a lot of weight and still have very little body fat! Of course, you'd need to do it for a very long period of time (for the D2O to replace all the H2O in your body). But would there be health risks? haha.
 
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I like the question and I think the full answer has to be very complicated.Something that comes immediately to mind is that as the D2O builds up the viscosity and other properties of blood and other body fluids will be adversely affected,and the heart ,kidneys and other organs will not be able to function as effectively and start to shut down.
 
The average atomic weight for H2O is about 18, and the average for D2O is about 20. You would add roughly 11% to the water weight you replace. I don't know if that qualifies as "A LOT."

The added weight would probably increase blood pressure, but it's hard to say if the viscosity would be affected very much. The chemistry shouldn't change either, since you wouldn't be changing the number of electrons.
 
The permeability of water and deuterium oxide through aquaporin-1, the main water channel in the body, is about equal:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2154366/

It's odd that deutrium inhibits cell division- I wonder if the effect isn't D2O, but rather the D ion replaces H in proteins etc. (hydrogen-deuterium exchange), altering the activities- I couldn't find a clear study,tho.

http://www.terraformers.org.au/deuterium.html
 
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My bet is that due to the isotopic effect speeds of reactions change, and they are getting "out of sync" - while situation in cells is always dynamic, they are in some sort of steady state or dynamic equilibrium. Deuterium disrupts this equilibrium, concentration of some things goes up, of some goes down - that's a serious problem.
 

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