this was widely reported in the past, but not commented on here https://www.sciencedaily.com/releases/2016/04/160422115320.htm based on http://journals.aps.org/prl/abstract/10.1103/PhysRevLett.116.161101 Search for Spectral Irregularities due to Photon–Axionlike-Particle Oscillations with the Fermi Large Area Telescope M. Ajello et al. (The Fermi-LAT Collaboration) Phys. Rev. Lett. 116, 161101 – Published 20 April 2016 Abstract We report on the search for spectral irregularities induced by oscillations between photons and axionlike-particles (ALPs) in the γ-ray spectrum of NGC 1275, the central galaxy of the Perseus cluster. Using 6 years of Fermi Large Area Telescope data, we find no evidence for ALPs and exclude couplings above 5×10−12GeV−1 for ALP masses 0.5≲ma≲5neV at 95% confidence. The limits are competitive with the sensitivity of planned laboratory experiments, and, together with other bounds, strongly constrain the possibility that ALPs can reduce the γ-ray opacity of the Universe. how strong are those bounds, how good are those results? note they only pertain to axions as stable cold dark matter. axions could exist but are unstable and decay. so cold dark matter hypothesis just in 2016 axion and axion-like particles ruled out by astrophysical observations sterile neutrinos ruled out by ice cube WIMPS large parameter space ruled out by LUX and PandaX SUSY-WIMPS large parameter space ruled out by LUX and PandaX WIMPS not produced nor detected by Large Hadron Collider anything else?