This has been bugging me for a while. Last month I narrowed my choices down two two very good graduate programs. I found that one program I didn't feel very comfortable, so I chose the other one, where I felt like I would be happier and fit in more and a project that seemed more interesting to me. Basically the advice everyone always gives on the interent. As far as the reputation of the overall programs go, they're equal. But I wonder if down the road, I'll regret not "sucking it up" and choosing the other school where I had been offered a postion in the lab of a Nobel laureate. This school was my dream school until I actually visited during open house, so maybe this is why I won't let go of the "what if?" state of mind. I did notice (just looking back on history) it seems easier to win the Nobel Prize and other awards and gain prestigious faculty positions if your PhD advisor was a laureate. Maybe it's just politics, but who's complaining if the politics work in their favor? I'm just tired of contemplating this alone and wanted someone else's opinion on the politics of the science community.