Most likely, yes. Proton decay is virtually guaranteed by simple symmetry arguments: some process created the protons, and the time reverse of that process would necessarily cause them to decay (note: it wouldn't quite be that simple, but that's the basic idea). The properties of that process may suppress it to an extremely low level (e.g. requiring a very massive intermediate particle, akin to how the masses of the weak force bosons suppresses the weak nuclear force), but simple arguments seem to indicate it's impossible to eliminate it entirely.