Effect of vasoconstriction and dilation on blood pressure

Click For Summary
SUMMARY

The discussion centers on the regulation of blood pressure through vasoconstriction and dilation, emphasizing their opposing effects on peripheral resistance and blood volume. Vasoconstriction increases peripheral resistance, which elevates blood pressure (bP), while a decrease in blood volume through constriction can lower bP. The conversation highlights that blood flow is influenced by vessel cross-sectional area and velocity, and that blood pressure is not uniform across constricted and unconstricted sites. Additionally, it notes that hypertension can arise from increased fluid volume due to sodium resorption in the kidneys, alongside other regulatory mechanisms.

PREREQUISITES
  • Understanding of cardiovascular physiology
  • Knowledge of blood pressure dynamics
  • Familiarity with vasoconstriction and vasodilation mechanisms
  • Basic concepts of fluid dynamics in biological systems
NEXT STEPS
  • Research the role of vasoactive substances in blood pressure regulation
  • Study the effects of sodium resorption on hypertension
  • Explore the relationship between peripheral resistance and blood volume
  • Learn about local autoregulation mechanisms in blood flow
USEFUL FOR

Medical students, cardiovascular researchers, healthcare professionals, and anyone interested in understanding blood pressure regulation mechanisms.

Jmiz
Messages
20
Reaction score
0
One way to regulate blood pressure is through vasoconstriction which in turn increases peripheral resistance, but also decrease the amount of blood that passes through the vessel. These two changes have opposite effects on blood pressure. So is it because the resistance increase effect lead to a greater increase of bP than the effect of having lower volume of blood passing through the constricted vessel, which would in turn decrease bP since less volume lead to less vapor pressure from blood that would act on the vessel walls?

Also since blood flow = velocity times cross area of vessel, what is the impact on blood flow due to vasoconstriction?

Since bP = force exerted on vessel walls by blood, wouldn't bP not be equal at the site of vasoconstriction compared to another unconstricted site?

Thanks
 
Biology news on Phys.org
If you constrict some veins or arteries, where does the blood go?
 
Ultimately, still back to the heart
 
Blood is effectively incompressible. If the volume in reduced is some region, it has to go somewhere.
 
Jmiz said:
One way to regulate blood pressure is through vasoconstriction which in turn increases peripheral resistance, but also decrease the amount of blood that passes through the vessel. <snip>

There are multiple mechanisms to regulate blood pressure- not just through modulating the peripheral resistance (primarily the arterioles), but also by control over total blood volume. Hormonal control (vasoactive substances) are one mechanism, but there are many including neuronal and local autoregulation. A primary cause of hypertension is increased fluid volume due to excessive resorption of Na in the kidney, which over time leads to increased peripheral resistance.

There are multiple ways to induce high blood pressure: holding blood volume constant and increasing the peripheral resistance, or holding the peripheral resistance constant and increasing blood volume.
 
  • Like
Likes   Reactions: jim mcnamara

Similar threads

  • · Replies 10 ·
Replies
10
Views
3K
  • · Replies 3 ·
Replies
3
Views
2K
Replies
4
Views
10K
Replies
18
Views
3K
Replies
5
Views
2K
  • · Replies 2 ·
Replies
2
Views
11K
  • · Replies 3 ·
Replies
3
Views
7K
  • · Replies 4 ·
Replies
4
Views
3K
  • · Replies 9 ·
Replies
9
Views
5K
  • · Replies 7 ·
Replies
7
Views
9K