well, the typical situation (where your coordinates are somewhat normal (ie, can be related somehow to the cartesian coordinate system in a time independent fashion) then the hamiltonian is the energy of the system.
ie, simple harmonic oscillator:
L=T-U= 1/2 m x'^2 - 1/2 k x^2
where m is the mass, k is the spring constant, the first term is the kinetic energy (1/2 m v^2) and the second term is the potential (1/2 k x^2)
in this case H=T+U = Kinetic Energy + Potential Energy = Total Energy = Constant