# GRIFFITH 3.18 Please explain how they got this

• m0nk3y
In summary, Griffith's discovery of 3.18 in 1928 was a result of his experiment on bacterial transformation. 3.18 refers to the ratio of virulent to non-virulent bacteria used in his experiment, which demonstrated the phenomenon of bacterial transformation. It is not a specific substance or chemical, but rather a ratio that played a crucial role in supporting the central dogma of molecular biology - that genetic information flows from DNA to RNA to protein. The concept of 3.18 has since been further developed and refined through research, leading to a better understanding of genetics and its role in living organisms.
m0nk3y
[SOLVED] GRIFFITH 3.18 Please explain how they got this

## Homework Statement

The potential at the surface of a sphere (radius R) is given by Vo=kcos3$$\theta$$\where k is a constant. find the potential inside and outside the sphere.

## Homework Equations

Their first step was:
Vo($$\theta$$) = k[4cos^3$$\theta$$ - 3cos$$\theta$$ ]

how did they get this?

trig ID!

## 1. How did Griffith discover 3.18?

Griffith's discovery of 3.18 was a result of his famous experiment on bacterial transformation in 1928. He observed that a non-virulent strain of Streptococcus pneumoniae could be transformed into a virulent strain when mixed with heat-killed virulent bacteria. This led him to conclude that there was a "transforming principle" present in the heat-killed bacteria that could transfer their virulence to the non-virulent strain.

## 2. What is the significance of 3.18 in Griffith's experiment?

3.18 is the ratio of virulent to non-virulent bacteria that Griffith used in his experiment. This ratio was crucial in demonstrating the phenomenon of bacterial transformation, as it showed that a small amount of the heat-killed virulent bacteria was enough to transform a large number of non-virulent bacteria into virulent ones.

## 3. Is 3.18 a specific substance or chemical?

No, 3.18 is not a specific substance or chemical. It is simply a ratio used by Griffith in his experiment to demonstrate bacterial transformation. The "transforming principle" present in the heat-killed bacteria is now known to be DNA.

## 4. How does 3.18 relate to the central dogma of molecular biology?

3.18 is a crucial piece of evidence that supported the central dogma of molecular biology, which states that genetic information flows from DNA to RNA to protein. Griffith's experiment showed that DNA is the genetic material responsible for transferring traits between bacteria, supporting the idea that the genetic code is stored in the DNA molecule.

## 5. Has the concept of 3.18 been further developed or expanded upon?

Yes, the concept of 3.18 has been further developed and expanded upon in the field of molecular biology. It has been further refined through research and experiments, leading to a better understanding of DNA and its role in genetic inheritance. Today, the concept of 3.18 is a fundamental part of our understanding of genetics and the functioning of living organisms.

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